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Cytokines and reagents that can be added to cell cultures and used to investigate a variety of cell pathways and metabolic processes. Products also include a variety of kits, immunoassays, arrays, and staining products for use in cytokine analysis experiments.
Interleukin-2 (IL-2) is an helical cytokine belonging to T-helper cell type 1. It has a molecular weight of 15kDa. The IL2 gene is mapped to human chromosome 4q27. IL-2 is originally called as T cell growth factor.
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CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA. CpG ODNs are recognized by Toll-like receptor 9 (TLR9) leading to strong immunostimulatory effects.
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The V-PLEX Plus Human Cytokine 30-plex Kit from Meso Scale Discovery is a multiplex immunoassay for measuring 30 human cytokines chemokines and growth factors in a small sample It includes a 96-well plate with capture antibodies detection antibodies with an electrochemiluminescent label and calibrator solutions The assay is sensitive has a broad range and uses only 25 L per well Results are ready in 3 5 hours with an MSD instrument This kit efficiently profiles cytokines and chemokines related to inflammation immune response and growth regulation
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